We examined the relationship between essential and toxic elements in the plasma of institutionalized older adults and their cholesterol levels. Focusing on a group of 149 Brazilian seniors living in nursing homes, our goal was to understand how these elements influence lipid profiles and blood sugar levels.
Our findings indicated that lower concentrations of certain chemical elements, particularly iron, seemed to protect against increasing total cholesterol levels. We observed non-linear effects of iron, along with other elements like barium and copper, on triglyceride levels. Notably, when the concentration of these elements fell below a certain threshold, we found an associated decrease in total cholesterol.
These results suggest that monitoring the levels of these essential and toxic elements could be vital in preventing dyslipidemia—a condition characterized by abnormal lipid levels—and managing clinical interventions in older adults. The significant role of iron in influencing cholesterol levels emphasizes the need for continued research and screening in this population, to ensure that their health remains a top priority.
Read More
2
Iron's harmful impact on cholesterol
High Consumption of Iron Exacerbates Hyperlipidemia, Atherosclerosis, and Female Sterility in Zebrafish via Acceleration of Glycation and Degradation of Serum Lipoproteins.
We looked into how high doses of iron impact cholesterol levels and overall health. By adding ferrous ions to cells and testing on zebrafish over several weeks, we noticed significant increases in cholesterol and triglyceride levels. Iron not only heightened these lipids but also led to more severe aging in cells and reduced reproductive abilities in female zebrafish. Unfortunately, it seems that rather than helping, iron could make high cholesterol and blood sugar issues worse, contributing to other health complications.
Read More
9
Bovine lactoferrin reduces cholesterol levels
Bovine lactoferrin ameliorates antioxidant esterase activity and 8-isoprostane levels in high-cholesterol-diet fed rats.
We aimed to evaluate the impact of bovine lactoferrin (bLF) on cholesterol levels and antioxidant activity in rats fed a high-cholesterol diet.
In our study, 44 male rats were divided into groups, including one that received bLF treatment over four weeks.
Notably, we observed that bLF led to a significant drop in harmful LDL cholesterol and triglycerides while raising beneficial HDL levels. Additionally, 8-isoprostane levels, a marker of oxidative stress, were substantially reduced.
These findings suggest that bLF may effectively combat cholesterol-associated oxidative stress.
Read More
Most Useful Reviews
10
Prevented hospitalisation
68 people found this helpful
This iron saved me from needing hospital treatment! When my haemoglobin was critically low at 70, my gastroenterologist recommended this product. I took large dosages, and thankfully did not face any side effects. My haemoglobin improved to 125 in just three weeks, and my ferritin level also rose significantly. I’m immensely grateful for this iron and its quality!
Read More
9
Boosted hemoglobin levels
61 people found this helpful
Excellent iron! Within a month, my hemoglobin increased from 106 to 131 g/l. Previous supplements only raised it by 2 units over two weeks. I’m incredibly grateful for this improvement!
Read More
9
Increased energy levels
36 people found this helpful
This excellent product, featuring iron in a bisglycinate chelated form, has significantly improved my haemoglobin levels. It is easily digestible, does not cause constipation, and has no side effects. After taking it, I feel more energetic and my overall energy levels have noticeably increased. My mother has also benefited from it.
We aimed to evaluate the impact of bovine lactoferrin (bLF) on cholesterol levels and antioxidant activity in rats fed a high-cholesterol diet.
In our study, 44 male rats were divided into groups, including one that received bLF treatment over four weeks.
Notably, we observed that bLF led to a significant drop in harmful LDL cholesterol and triglycerides while raising beneficial HDL levels. Additionally, 8-isoprostane levels, a marker of oxidative stress, were substantially reduced.
These findings suggest that bLF may effectively combat cholesterol-associated oxidative stress.
Read More
8
Quail eggs improve maternal health
The effect of quail egg supplements enriched with marine macroalgae spinosum on the physiological condition of Sprague Dawley rats during pregnancy.
We began by investigating how quail egg supplements enriched with marine macroalgae might influence body weight and other physiological conditions in pregnant rats. Our study involved 25 Sprague Dawley rats split into five groups, each receiving different diets, including a control group and groups that consumed quail eggs from quail fed varying percentages of macroalgae.
The results revealed that the addition of marine macroalgae, particularly at concentrations of 3%, 4%, and 5%, led to significant changes in the nutritional profile of the quail eggs. Notably, we observed an increase in iron levels, which is often considered beneficial for various physiological processes. Interestingly, these dietary changes also contributed to a decrease in cholesterol levels.
While we did see improvements in various health markers such as hemoglobin and hematocrit, which are crucial during pregnancy, it's essential to approach the findings with caution. Although iron levels went up and cholesterol levels went down in the context of this study, isolating the impact of iron alone on high cholesterol is tricky since it was part of a combined nutrient effect from the quail egg supplements.
In summary, while iron from the enriched quail eggs appears to contribute positively to the rats' physiological health, the direct relationship between iron supplementation and lower cholesterol levels requires further investigation.
Read More
8
Iron's influence on cholesterol levels
Association between exposure to plasma mixture of essential and toxic elements and the lipid profile in institutionalized older adults.
We examined the relationship between essential and toxic elements in the plasma of institutionalized older adults and their cholesterol levels. Focusing on a group of 149 Brazilian seniors living in nursing homes, our goal was to understand how these elements influence lipid profiles and blood sugar levels.
Our findings indicated that lower concentrations of certain chemical elements, particularly iron, seemed to protect against increasing total cholesterol levels. We observed non-linear effects of iron, along with other elements like barium and copper, on triglyceride levels. Notably, when the concentration of these elements fell below a certain threshold, we found an associated decrease in total cholesterol.
These results suggest that monitoring the levels of these essential and toxic elements could be vital in preventing dyslipidemia—a condition characterized by abnormal lipid levels—and managing clinical interventions in older adults. The significant role of iron in influencing cholesterol levels emphasizes the need for continued research and screening in this population, to ensure that their health remains a top priority.
Read More
7
Iron Levels and Cholesterol Relationship
Relationship Between Whole Blood Iron Levels and Lipid Profile Parameters in the General Population: Findings from Routine Physical Examination Report.
Our study explored the relationship between whole blood iron levels and cholesterol in a community in Taizhou, China, involving 1,917 participants. We looked specifically at how iron levels might connect with various lipid profile parameters, including total cholesterol and triglycerides.
We found that whole blood iron concentration was positively correlated with total cholesterol, triglycerides, and low-density lipoprotein (LDL) cholesterol for both men and women. The most significant association was observed with triglycerides. However, we did not see a correlation between iron levels and high-density lipoprotein (HDL) cholesterol.
Interestingly, the positive correlations were stronger in men compared to women. While our findings suggest that managing iron levels could be a potential strategy for controlling cholesterol levels, the study does not indicate that iron treatment directly lowers high cholesterol. Therefore, any potential dietary or therapeutic strategies involving iron need to be considered carefully.
Our results might help inform healthcare providers about managing cholesterol and dyslipidemia in the population, especially among males.
Read More
4
Iron-Copper Balance Affects Cholesterol
High Iron Consumption Modifies the Hepatic Transcriptome Related to Cholesterol Metabolism.
We investigated how dietary iron impacts cholesterol metabolism and the role of copper in this process. Using a rat model, we conducted experiments with varying iron and copper amounts to see how these elements interact in the body.
Our findings revealed that a high intake of iron, especially when copper levels were low, led to an increase in cholesterol levels—a condition known as hypercholesterolemia. This shift in cholesterol metabolism also resulted in changes to gene expression linked to lipids, increasing risks for cardiovascular diseases.
Interestingly, when we supplemented copper in the diet, we noticed positive changes that helped reduce these negative effects associated with high iron intake. The data showed that significant gene activity related to cholesterol synthesis increased with high iron consumption, while pathways responsible for cholesterol elimination decreased.
Ultimately, our study highlights the crucial balance needed between iron and copper in maintaining healthy cholesterol levels. It shows that while iron can be beneficial in addressing deficiencies, its excess can cause complications, emphasizing the importance of a balanced diet.
This iron saved me from needing hospital treatment! When my haemoglobin was critically low at 70, my gastroenterologist recommended this product. I took large dosages, and thankfully did not face any side effects. My haemoglobin improved to 125 in just three weeks, and my ferritin level also rose significantly. I’m immensely grateful for this iron and its quality!
Read More
9
Boosted hemoglobin levels
61 people found this helpful
Excellent iron! Within a month, my hemoglobin increased from 106 to 131 g/l. Previous supplements only raised it by 2 units over two weeks. I’m incredibly grateful for this improvement!
Read More
9
Increased energy levels
36 people found this helpful
This excellent product, featuring iron in a bisglycinate chelated form, has significantly improved my haemoglobin levels. It is easily digestible, does not cause constipation, and has no side effects. After taking it, I feel more energetic and my overall energy levels have noticeably increased. My mother has also benefited from it.
Read More
10
Miraculous effects noted
12 people found this helpful
While pregnant, I faced severe anaemia and nearly required a blood transfusion. My doctor suggested trying this supplement, and it worked wonders! My anaemia resolved, and my blood values returned to normal. I experienced no stomach discomfort, truly a gentle product which I highly recommend for low iron levels.
Read More
9
Significant results!
11 people found this helpful
This iron has raised my hemoglobin and ferritin swiftly! Within a month, my levels dramatically improved, unlike previous products. I feel revitalised and my immunity is much better. I highly recommend this supplement as the benefits are evident.
High cholesterol, or hyperlipidemia, is a medical condition characterized by an elevated level of cholesterol in the bloodstream. Cholesterol is a waxy, fat-like substance that’s essential for building healthy cells, but too much of it can lead to serious health issues, including heart disease and stroke. Cholesterol is carried through the blood by lipoproteins, with two main types being low-density lipoprotein (LDL) and high-density lipoprotein (HDL). LDL, often referred to as "bad" cholesterol, can lead to the buildup of plaque in the arteries, while HDL, known as "good" cholesterol, helps carry cholesterol away from the arteries and back to the liver.
Factors contributing to high cholesterol can include poor diet, lack of exercise, obesity, smoking, and genetic predisposition. Regular health screenings are crucial, as high cholesterol often presents no overt symptoms. Maintaining a heart-healthy diet rich in fruits, vegetables, whole grains, and healthy fats, coupled with regular physical activity and avoiding tobacco, can help manage cholesterol levels effectively. In some cases, medications may be necessary to control high cholesterol, so consulting with a healthcare provider is key for tailored advice.
Iron is a chemical element with the symbol Fe, derived from the Latin word "ferrum." It is a metal that is known for its strength and versatility, making it one of the most widely used materials in construction, manufacturing, and various industrial applications. Iron is the fourth most abundant element in the universe by mass and is primarily obtained through the mining of iron ores, such as hematite and magnetite. Once mined, it undergoes processes like smelting and refining to produce usable forms like cast iron, wrought iron, and steel.
In addition to its industrial uses, iron is also crucial for human health, as it plays a significant role in the production of hemoglobin, the protein in red blood cells responsible for transporting oxygen throughout the body. A deficiency in iron can lead to anemia, characterized by fatigue and weakened immunity. Overall, iron is a fundamental element that supports modern infrastructure and is vital for maintaining good health.
Based on user reviews, those taking this supplement for high cholesterol report varying timelines for seeing noticeable results. A number of users mention improvements within a month of starting the supplement. For instance, one user noted a significant increase in their ferritin levels in just two months after switching to this iron supplement, while another reported a marked improvement after only one month (Read Review; Read Review).
However, some users indicated that it might take longer to see the full benefits; for example, one review highlighted a gradual improvement over three months, showing that individual responses can vary widely (Read Review). Overall, while many users report quick results, a consistent pattern suggests that some may take several weeks to months to experience significant changes in their cholesterol levels.
The evidence surrounding the impact of iron on cholesterol levels reveals a complex relationship that is not fully supportive of using iron supplements for managing high cholesterol. Research indicates that while dietary iron can influence cholesterol metabolism, it does not consistently lead to lower cholesterol levels. For example, one study found a positive correlation between whole blood iron levels and total cholesterol and triglycerides, suggesting that higher iron may relate to increased cholesterol levels rather than a decrease [2]. Furthermore, another study indicated that excess iron worsens cholesterol levels and can contribute to health complications, indicating that high doses of iron may not be beneficial for those with high cholesterol [6].
On the other hand, certain studies show that iron may have protective effects in specific contexts, such as lower concentrations being associated with decreases in overall cholesterol in older adults [3]. However, these positive findings are inconclusive and suggest the need for a balanced approach to iron intake. Overall, the current scientific literature does not provide a strong endorsement for using iron as a supplement specifically for high cholesterol management, highlighting the need for further research to clarify these relationships and potential therapeutic strategies.
Many users have reported significant improvements in their symptoms after using this particular iron supplement, with individual results varying widely. For instance, one user noted a rapid increase in hemoglobin from a critically low 70 to 125 in just three weeks, attributing their recovery from severe anemia to the supplement (Read Review). Another shared a similar experience, with their hemoglobin rising from 106 to 131 g/l within a month, underscoring the supplement's effectiveness compared to previous attempts with other products (Read Review).
Users have also highlighted enhanced overall well-being beyond just increased hemoglobin levels. Some reported boosts in energy and vitality, with one user mentioning a return to normal blood values and no stomach discomfort after struggling with severe anemia during pregnancy (Read Review). Additionally, several reviews indicate a significant reduction in symptoms like hair loss and fatigue, with users feeling more invigorated and alert (Read Review; Read Review). Collectively, these experiences suggest that many users have achieved substantial and rapid improvements in their iron status and associated symptoms.
Based on user reviews, many individuals report positive outcomes when combining this iron supplement with other products, particularly vitamin C, to enhance absorption. One user highlighted the effectiveness of taking iron alongside vitamin C while also avoiding dairy products, resulting in significant improvements in their ferritin levels without any digestive issues (Read Review). Another user achieved remarkable results by pairing this iron with other brands such as Solgar and Jarrow Formulas, noting a substantial increase in hemoglobin over three months (Read Review).
Additionally, users praised the product's compatibility with L-Lysine for better results while managing cholesterol and anemia. Reviews emphasized that combining this supplement with compatible nutrients facilitated a much-improved absorption rate, helping to achieve desired therapeutic outcomes without the common gastrointestinal side effects typically associated with iron supplements (Read Review). Overall, these insights suggest that users have found beneficial synergies when combining this iron supplement with other nutrients to better manage their health conditions.
Users report that the appropriate dosage of iron for treating iron deficiency can vary significantly, depending on individual needs and health conditions. Some users have found success with larger dosages, noting improvements in haemoglobin and ferritin levels within just a few weeks of use. For instance, one reviewer mentioned their haemoglobin rose from a critically low 70 to 125 in just three weeks after taking high doses, demonstrating the potential efficiency of higher dosages for individuals with severe deficiencies Read Review. Another user noted that taking two capsules daily during pregnancy led to remarkable improvements in their iron levels, which emphasizes the importance of dosage in relation to specific conditions Read Review.
Moreover, some users advocate for maintaining a balanced approach to dosage, suggesting the use of additional supplements like vitamin C to enhance iron absorption and improve results. A user mentioned that they took iron alongside vitamin C while avoiding dairy products for optimal absorption, indicating that dosage can also be influenced by dietary considerations Read Review. Overall, users appear to find a dosage that works for them through trial and testing, closely monitoring their levels with healthcare professionals to optimize treatment outcomes.
9
Ferritin significantly raised
1 people found this helpful
After switching to this Solgar iron supplement, I experienced a considerable increase in ferritin levels within two months, moving from 33 to 59 mcg/l. Unlike previous brands, this one did not lead to digestive issues and has proven to be effective.
9
Significant results!
11 people found this helpful
This iron has raised my hemoglobin and ferritin swiftly! Within a month, my levels dramatically improved, unlike previous products. I feel revitalised and my immunity is much better. I highly recommend this supplement as the benefits are evident.
9
Cramps resolved
2 people found this helpful
Great product!!! I was surprised at how effective it is. After my blood test revealed I was anaemic and suffering from cramps and hand numbness, I started taking this supplement with Solgar and Jarrow Formulas. After three months, my haemoglobin rose dramatically from 80 to 123! I'm absolutely shocked and highly recommend it.
10
Prevented hospitalisation
68 people found this helpful
This iron saved me from needing hospital treatment! When my haemoglobin was critically low at 70, my gastroenterologist recommended this product. I took large dosages, and thankfully did not face any side effects. My haemoglobin improved to 125 in just three weeks, and my ferritin level also rose significantly. I’m immensely grateful for this iron and its quality!
9
Boosted hemoglobin levels
61 people found this helpful
Excellent iron! Within a month, my hemoglobin increased from 106 to 131 g/l. Previous supplements only raised it by 2 units over two weeks. I’m incredibly grateful for this improvement!
10
Miraculous effects noted
12 people found this helpful
While pregnant, I faced severe anaemia and nearly required a blood transfusion. My doctor suggested trying this supplement, and it worked wonders! My anaemia resolved, and my blood values returned to normal. I experienced no stomach discomfort, truly a gentle product which I highly recommend for low iron levels.
6
Stopped hair loss
10 people found this helpful
I had a problem with hair loss, exacerbated by antibiotics. Nothing worked until I started taking iron with vitamin C, which stopped the loss almost immediately. There’s also an overall sense of cheerfulness; I believe my iron levels were critically low despite high hemoglobin. I recommend this for anyone facing similar issues.
9
Increased energy levels
36 people found this helpful
This excellent product, featuring iron in a bisglycinate chelated form, has significantly improved my haemoglobin levels. It is easily digestible, does not cause constipation, and has no side effects. After taking it, I feel more energetic and my overall energy levels have noticeably increased. My mother has also benefited from it.
9
Improved iron levels
2 people found this helpful
HEY, CHECK OUT MY RESULTS! My iron level improved significantly over 2.5 to 3 months, going from 12.9 to 30. I prefer glass bottles for supplements, as they're safer and keep the ingredients intact. The capsules dissolve better in the intestine rather than the stomach, enhancing absorption. I found them easy to swallow and pleasant in taste. I took the iron alongside vitamin C to facilitate absorption and experienced excellent results, without stomach problems. It's essential to monitor Ferritin as well, since it reflects iron storage in the body. I suggest taking iron away from dairy products for best absorption.
9
Effective iron supplement
1 people found this helpful
Probably the best and most effective iron supplement. Within a month of use, my blood test results showed noticeable improvement. For better absorption, I took it with L-Lysine (in the evening on an empty stomach). The result is GREAT! There are no gastrointestinal side effects. I highly recommend it to anyone currently treating high cholesterol or anaemia.
9
Effective during pregnancy
1 people found this helpful
While pregnant with twins, my iron needs peaked. I tried various supplements, but all caused constipation. Gentle Iron was a game changer! After a month of taking two capsules daily, my haemoglobin rose from 105 to 134 and ferritin from 31 to 54. I continue taking one capsule daily now with no constipation.
7
Iron Levels and Cholesterol Relationship
Relationship Between Whole Blood Iron Levels and Lipid Profile Parameters in the General Population: Findings from Routine Physical Examination Report.
Our study explored the relationship between whole blood iron levels and cholesterol in a community in Taizhou, China, involving 1,917 participants. We looked specifically at how iron levels might connect with various lipid profile parameters, including total cholesterol and triglycerides.
We found that whole blood iron concentration was positively correlated with total cholesterol, triglycerides, and low-density lipoprotein (LDL) cholesterol for both men and women. The most significant association was observed with triglycerides. However, we did not see a correlation between iron levels and high-density lipoprotein (HDL) cholesterol.
Interestingly, the positive correlations were stronger in men compared to women. While our findings suggest that managing iron levels could be a potential strategy for controlling cholesterol levels, the study does not indicate that iron treatment directly lowers high cholesterol. Therefore, any potential dietary or therapeutic strategies involving iron need to be considered carefully.
Our results might help inform healthcare providers about managing cholesterol and dyslipidemia in the population, especially among males.
2
Iron's harmful impact on cholesterol
High Consumption of Iron Exacerbates Hyperlipidemia, Atherosclerosis, and Female Sterility in Zebrafish via Acceleration of Glycation and Degradation of Serum Lipoproteins.
We looked into how high doses of iron impact cholesterol levels and overall health. By adding ferrous ions to cells and testing on zebrafish over several weeks, we noticed significant increases in cholesterol and triglyceride levels. Iron not only heightened these lipids but also led to more severe aging in cells and reduced reproductive abilities in female zebrafish. Unfortunately, it seems that rather than helping, iron could make high cholesterol and blood sugar issues worse, contributing to other health complications.
8
Iron's influence on cholesterol levels
Association between exposure to plasma mixture of essential and toxic elements and the lipid profile in institutionalized older adults.
We examined the relationship between essential and toxic elements in the plasma of institutionalized older adults and their cholesterol levels. Focusing on a group of 149 Brazilian seniors living in nursing homes, our goal was to understand how these elements influence lipid profiles and blood sugar levels.
Our findings indicated that lower concentrations of certain chemical elements, particularly iron, seemed to protect against increasing total cholesterol levels. We observed non-linear effects of iron, along with other elements like barium and copper, on triglyceride levels. Notably, when the concentration of these elements fell below a certain threshold, we found an associated decrease in total cholesterol.
These results suggest that monitoring the levels of these essential and toxic elements could be vital in preventing dyslipidemia—a condition characterized by abnormal lipid levels—and managing clinical interventions in older adults. The significant role of iron in influencing cholesterol levels emphasizes the need for continued research and screening in this population, to ensure that their health remains a top priority.
References
Basri H, Widiyanto S, Saragih HTS, Zuprizal Z. The effect of quail egg supplements enriched with marine macroalgae spinosum on the physiological condition of Sprague Dawley rats during pregnancy. J Adv Vet Anim Res. 2024;11:1114. doi:10.5455/javar.2024.k862
Pan RJ, Luo Z, You YS, Wang JD, Chen YQ, et al. Relationship Between Whole Blood Iron Levels and Lipid Profile Parameters in the General Population: Findings from Routine Physical Examination Report. Biol Trace Elem Res. 2024. doi:10.1007/s12011-024-04459-z
Pacheco DA, de Sousa Campêlo AL, de Sousa SES, Sales MC, Sena-Evangelista KCM, et al. Association between exposure to plasma mixture of essential and toxic elements and the lipid profile in institutionalized older adults. J Trace Elem Med Biol. 2024;85:127490. doi:10.1016/j.jtemb.2024.127490
Lee J, Jang H, Doo M, Kim BH, Ha JH. High Iron Consumption Modifies the Hepatic Transcriptome Related to Cholesterol Metabolism. J Med Food. 2024;27:895. doi:10.1089/jmf.2024.k.0139
Faridvand Y, Nozari S, Asoudeh-Fard A, Karimi MA, Pezeshkian M, et al. Bovine lactoferrin ameliorates antioxidant esterase activity and 8-isoprostane levels in high-cholesterol-diet fed rats. Int J Vitam Nutr Res. 2017;87:201. doi:10.1024/0300-9831/a000516
Kim SH, Yadav D, Kim SJ, Kim JR, Cho KH. High Consumption of Iron Exacerbates Hyperlipidemia, Atherosclerosis, and Female Sterility in Zebrafish via Acceleration of Glycation and Degradation of Serum Lipoproteins. Nutrients. 2017;9. doi:10.3390/nu9070690